Human CD303/CLEC4C protein (Recombinant) (N-His) (STJP005751)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CD303/CLEC4C-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | CLEC4C |
| Gene ID | 170482 |
| Uniprot ID | CLC4C_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ser67-Ile213 |
Additional Info
| Function | Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cells. Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man. Binds to serum IgG. Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium. |
| Protein Name | C-Type Lectin Domain Family 4 Member CBlood Dendritic Cell Antigen 2Bdca-2C-Type Lectin Superfamily Member 7Dendritic LectinCd Antigen Cd303 |
| Database Links | Reactome: R-HSA-5621480Reactome: R-HSA-6798695 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane Protein |
| Alternative Protein Names | C-Type Lectin Domain Family 4 Member C proteinBlood Dendritic Cell Antigen 2 proteinBdca-2 proteinC-Type Lectin Superfamily Member 7 proteinDendritic Lectin proteinCd Antigen Cd303 proteinCLEC4C proteinBDCA2 proteinCLECSF11 proteinCLECSF7 proteinDLEC proteinHECL proteinUNQ9361 proteinPRO34150 protein |
Information sourced from Uniprot.org