Human CD300A protein (Recombinant) (His-Tag) (STJP018337)

Name: Human CD300A protein (Recombinant) (His-Tag) (STJP018337)
SKU: STJP018337
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostE.coli

ImmunogenHuman

STJP018337

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Short Description	Recombinant-Human CD300A-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications	SDS-PAGE
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration	0.5 mg/mL
Formulation	Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% Glycerol, 1mM DTT
Storage Instruction	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Gene Symbol	CD300A
Gene ID	11314
Uniprot ID	CLM8_HUMAN
Accession Number	NP_009192
Immunogen	Human
Immunogen Region	18-128aa
Immunogen Sequence	LSKCRTV AGPVGGSLSV QCPYEKEHRT LNKYWCRPPQ IFLCDKIVET KGSAGKRNGR VSIRDSPANL SFTVTLENLT EEDAGTYWCG VDTPWLRDFH DPVVEVEVSV FPAS

Tissue Specificity	Expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes.
Post Translational Modifications	Phosphorylated on tyrosine. N-glycosylated.
Function	Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation. Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 but not TRIF through activation of PTPN6.
Protein Name	Cmrf35-Like Molecule 8 Clm-8 Cd300 Antigen-Like Family Member A Cmrf-35-H9 Cmrf35-H9 Cmrf35-H Irc1/Irc2 Immunoglobulin Superfamily Member 12 Igsf12 Inhibitory Receptor Protein 60 Irp60 Nk Inhibitory Receptor Cd Antigen Cd300a
Database Links	Reactome: R-HSA-198933 Reactome: R-HSA-6798695
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein
Alternative Protein Names	Cmrf35-Like Molecule 8 protein Clm-8 protein Cd300 Antigen-Like Family Member A protein Cmrf-35-H9 protein Cmrf35-H9 protein Cmrf35-H protein Irc1/Irc2 protein Immunoglobulin Superfamily Member 12 protein Igsf12 protein Inhibitory Receptor Protein 60 protein Irp60 protein Nk Inhibitory Receptor protein Cd Antigen Cd300a protein CD300A protein CMRF35H protein IGSF12 protein HSPC083 protein

Information sourced from Uniprot.org