Human CD300a protein (Recombinant) (C-Fc-His) (STJP013608)

Name: Human CD300a protein (Recombinant) (C-Fc-His) (STJP013608)
SKU: STJP013608-100
Price: 503.5 GBP
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostMammalian Cells

ConjugationUnconjugated

ImmunogenHomo sapiens (Human)

STJP013608-100

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Short Description	Recombinant-Human CD300a-C-Fc-His protein was developed from mammalian cells and has a target region of C-Fc-His. For use in research applications.
Applications	ELISA/WB
Host	Mammalian Cells
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Conjugation	Unconjugated
Dilution Range	Reconstitute in sterile water for a stock solution.
Formulation	Lyophilized from a 0.22 Mu m filtered solution in 20mM Tris-HCl, 150mM NaCl, 5% Trehalose, pH 8.0.
Storage Instruction	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin	< 1 EU/µg as determined by LAL test.

Post Translational Modifications	Phosphorylated on tyrosine. N-glycosylated.
Function	Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation. Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 but not TRIF through activation of PTPN6.
Protein Name	Cmrf35-Like Molecule 8 Clm-8 Cd300 Antigen-Like Family Member A Cmrf-35-H9 Cmrf35-H9 Cmrf35-H Irc1/Irc2 Immunoglobulin Superfamily Member 12 Igsf12 Inhibitory Receptor Protein 60 Irp60 Nk Inhibitory Receptor Cd Antigen Cd300a
Database Links	Reactome: R-HSA-198933 Reactome: R-HSA-6798695
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein
Alternative Protein Names	Cmrf35-Like Molecule 8 protein Clm-8 protein Cd300 Antigen-Like Family Member A protein Cmrf-35-H9 protein Cmrf35-H9 protein Cmrf35-H protein Irc1/Irc2 protein Immunoglobulin Superfamily Member 12 protein Igsf12 protein Inhibitory Receptor Protein 60 protein Irp60 protein Nk Inhibitory Receptor protein Cd Antigen Cd300a protein CD300A protein CMRF35H protein IGSF12 protein HSPC083 protein

Information sourced from Uniprot.org