Human CD30/TNFRSF8 protein (Recombinant) (His-Tag) (STJP018083)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human CD30/TNFRSF8-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% Glycerol, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TNFRSF8 |
| Gene ID | 943 |
| Uniprot ID | TNR8_HUMAN |
| Accession Number | NP_001234.1 |
| Immunogen | Human |
| Immunogen Region | 19-379aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Isoform 2: Detected in alveolar macrophages (at protein level). |
| Post Translational Modifications | Phosphorylated on serine and tyrosine residues (Probable). Isoform 2 is constitutively phosphorylated. |
| Function | Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 8Cd30l ReceptorKi-1 AntigenLymphocyte Activation Antigen Cd30Cd Antigen Cd30 |
| Database Links | Reactome: R-HSA-5669034 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Cytoplasm |
| Alternative Protein Names | Tumor Necrosis Factor Receptor Superfamily Member 8 proteinCd30l Receptor proteinKi-1 Antigen proteinLymphocyte Activation Antigen Cd30 proteinCd Antigen Cd30 proteinTNFRSF8 proteinCD30 proteinD1S166E protein |
Information sourced from Uniprot.org