Human CD292/BMPR1A protein (Recombinant) (N-His-SUMO) (STJP010063)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CD292/BMPR1A-N-His-SUMO protein was developed from e.coli for the region N-His-SUMO. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | BMPR1A |
| Gene ID | 657 |
| Uniprot ID | BMR1A_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Tyr179-Ile378 |
Additional Info
| Post Translational Modifications | Glycosylated. |
| Function | On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6. May promote the expression of HAMP, potentially via its interaction with BMP2. |
| Protein Name | Bone Morphogenetic Protein Receptor Type-1aBmp Type-1a ReceptorBmpr-1aActivin Receptor-Like Kinase 3Alk-3Serine/Threonine-Protein Kinase Receptor R5Skr5Cd Antigen Cd292 |
| Database Links | Reactome: R-HSA-201451 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCell Surface |
| Alternative Protein Names | Bone Morphogenetic Protein Receptor Type-1a proteinBmp Type-1a Receptor proteinBmpr-1a proteinActivin Receptor-Like Kinase 3 proteinAlk-3 proteinSerine/Threonine-Protein Kinase Receptor R5 proteinSkr5 proteinCd Antigen Cd292 proteinBMPR1A proteinACVRLK3 proteinALK3 protein |
Information sourced from Uniprot.org