Human CD292/BMPR1A protein (Recombinant) (C-Fc-His) (STJP013320)

Name: Human CD292/BMPR1A protein (Recombinant) (C-Fc-His) (STJP013320)
SKU: STJP013320-100
Price: 627.21 USD
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostMammalian Cells

ConjugationUnconjugated

ImmunogenHomo sapiens (Human)

STJP013320-100

Current Stock:

🚚 Free UK Delivery on orders over £150

Quantity:

Processing The item has been added

Enquire For Bulk Order

✓ 1-Year Performance Guarantee | SDS & Datasheet Included | Expert Tech Support | Covered by St John's Laboratory Guarantee

Short Description	Recombinant-Human CD292/BMPR1A-C-Fc-His protein was developed from mammalian cells and has a target region of C-Fc-His. For use in research applications.
Applications	ELISA/WB
Host	Mammalian Cells
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Conjugation	Unconjugated
Dilution Range	Reconstitute in sterile water for a stock solution.
Formulation	Lyophilized from a 0.22 Mu m filtered solution in PBS, pH 7.4.
Storage Instruction	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin	< 1 EU/µg as determined by LAL test.

Post Translational Modifications	Glycosylated.
Function	On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6. May promote the expression of HAMP, potentially via its interaction with BMP2.
Protein Name	Bone Morphogenetic Protein Receptor Type-1a Bmp Type-1a Receptor Bmpr-1a Activin Receptor-Like Kinase 3 Alk-3 Serine/Threonine-Protein Kinase Receptor R5 Skr5 Cd Antigen Cd292
Database Links	Reactome: R-HSA-201451
Cellular Localisation	Cell Membrane Single-Pass Type I Membrane Protein Cell Surface
Alternative Protein Names	Bone Morphogenetic Protein Receptor Type-1a protein Bmp Type-1a Receptor protein Bmpr-1a protein Activin Receptor-Like Kinase 3 protein Alk-3 protein Serine/Threonine-Protein Kinase Receptor R5 protein Skr5 protein Cd Antigen Cd292 protein BMPR1A protein ACVRLK3 protein ALK3 protein

Information sourced from Uniprot.org