Human CD277/BTN3A1 protein (Recombinant-Active) (C-hFc-His) (STJP011715)
SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Active-Human CD277/BTN3A1-C-hFc-His protein was developed from mammalian cells and has a target region of C-hFc-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | <0.1 EU/Mu g of the protein by the LAL method. |
| Immunoreactivity | Measured by its ability to inhibit Anti-CD3-induced proliferation of jurkat. The ED50 for this effect is 20-100 ng/mL. |
Target Information
| Gene Symbol | BTN3A1 |
| Gene ID | 11119 |
| Uniprot ID | BT3A1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Gln30-Gly254 |
Additional Info
| Post Translational Modifications | N-glycosylated. |
| Function | Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate. |
| Protein Name | Butyrophilin Subfamily 3 Member A1Cd Antigen Cd277 |
| Database Links | Reactome: R-HSA-8851680 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Butyrophilin Subfamily 3 Member A1 proteinCd Antigen Cd277 proteinBTN3A1 proteinBTF5 protein |
Information sourced from Uniprot.org