Human CD256/TNFSF13/APRIL protein (Recombinant-Active) (N-His) (STJP011748)
SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Active-Human CD256/TNFSF13/APRIL-N-His protein was developed from mammalian cells and has a target region of N-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | <0.1 EU/Mu g of the protein by the LAL method. |
| Immunoreactivity | Recombinant human CD256/TNFSF13/APRIL can induces mouse B cell proliferation. The ED50 for this effect is 10-30 ng/mL. |
Target Information
| Gene Symbol | TNFSF13 |
| Gene ID | 8741 |
| Uniprot ID | TNF13_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Lys112-Leu250 |
Additional Info
| Post Translational Modifications | The precursor is cleaved by furin. |
| Function | Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. Plays a role in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes. |
| Protein Name | Tumor Necrosis Factor Ligand Superfamily Member 13A Proliferation-Inducing LigandAprilTnf- And Apol-Related Leukocyte Expressed Ligand 2Tall-2Tnf-Related Death Ligand 1Trdl-1Cd Antigen Cd256 |
| Database Links | Reactome: R-HSA-450520Reactome: R-HSA-5669034 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Tumor Necrosis Factor Ligand Superfamily Member 13 proteinA Proliferation-Inducing Ligand proteinApril proteinTnf- And Apol-Related Leukocyte Expressed Ligand 2 proteinTall-2 proteinTnf-Related Death Ligand 1 proteinTrdl-1 proteinCd Antigen Cd256 proteinTNFSF13 proteinAPRIL proteinTALL2 proteinZTNF2 proteinUNQ383 proteinPRO715 protein |
Information sourced from Uniprot.org