Biotinylated Human CD24 on Tris-Bis PAGE under reduced conditions. The purity is greater than 95%.

Human CD24 protein (Recombinant) (C-mFc) {Biotin} (STJP001668)

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STJP001668
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Host: HEK293
Note: STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CD24-C-mFc protein was developed from hek293 and has a target region of C-mFc. For use in research applications.
Conjugation: Biotin
Formulation: Lyophilised from 0.2 µm filtered PBS solution pH7.4.
Dilution Range: Upon receipt centrifuge vial to ensure maximal product extraction, recommended: 20sec, 5K RPM
Storage Instruction: The lyophilized protein is stable for at least 1 year from date of receipt at-20°C.
Endotoxin: Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg).
Gene Symbol: CD24
Gene ID: 100133941
Uniprot ID: CD24_HUMAN
Immunogen Region: Ser27-Gly59
Immunogen: DNA sequence encoding Human CD24 (Primary Amine Labeling) including a C-mFc tag was expressed in HEK293 Cells. The recombinant protein was then biotinylated site specific using the AVItag biotinylation technology.
Post Translational Modifications Extensively O-glycosylated.
Function May have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells. In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. Plays a role in the control of autoimmunity.
Protein Name Signal Transducer Cd24
Small Cell Lung Carcinoma Cluster 4 Antigen
Cd Antigen Cd24
Database Links Reactome: R-HSA-373760
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Alternative Protein Names Signal Transducer Cd24 protein
Small Cell Lung Carcinoma Cluster 4 Antigen protein
Cd Antigen Cd24 protein
CD24 protein
CD24A protein

Information sourced from Uniprot.org

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