Human CD24 protein (Recombinant) (C-Fc) (STJP004411)
SPECIFICATIONS
HostMammalian Cells
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CD24-C-Fc protein was developed from mammalian cells for the region C-Fc. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | CD24 |
| Gene ID | 100133941 |
| Uniprot ID | CD24_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Ala57 |
Additional Info
| Post Translational Modifications | Extensively O-glycosylated. |
| Function | May have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells. In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. Plays a role in the control of autoimmunity. |
| Protein Name | Signal Transducer Cd24Small Cell Lung Carcinoma Cluster 4 AntigenCd Antigen Cd24 |
| Database Links | Reactome: R-HSA-373760 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-Anchor |
| Alternative Protein Names | Signal Transducer Cd24 proteinSmall Cell Lung Carcinoma Cluster 4 Antigen proteinCd Antigen Cd24 proteinCD24 proteinCD24A protein |
Information sourced from Uniprot.org