Human CD235a/GYPA protein (Recombinant) (N-His-KSI) (STJP010573)

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STJP010573
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Host: E. coli
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Recombinant-Human CD235a/GYPA-N-His-KSI protein was developed from e. coli and has a target region of N-His-KSI. For use in research applications.
Formulation: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.
Gene Symbol: GYPA
Gene ID: 2993
Uniprot ID: GLPA_HUMAN
Immunogen Region: Ser20-Glu91
Immunogen: Homo sapiens (Human)
Function Component of the ankyrin-1 complex, a multiprotein complex involved in the stability and shape of the erythrocyte membrane. Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. (Microbial infection) Appears to be a receptor for Hepatitis A virus (HAV). (Microbial infection) Receptor for P.falciparum erythrocyte-binding antigen 175 (EBA-175).binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans.
Protein Name Glycophorin-A
Mn Sialoglycoprotein
Pas-2
Sialoglycoprotein Alpha
Cd Antigen Cd235a
Database Links Reactome: R-HSA-202733
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Appears To Be Colocalized With Slc4a1
Alternative Protein Names Glycophorin-A protein
Mn Sialoglycoprotein
Pas-2 protein
Sialoglycoprotein Alpha protein
Cd Antigen Cd235a protein
GYPA protein
GPA protein
MNS protein

Information sourced from Uniprot.org

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