Human CD218b/IL18RAP protein (Recombinant) (C-Fc-His) (STJP013014)
SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CD218b/IL18RAP-C-Fc-His protein was developed from mammalian cells and has a target region of C-Fc-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a 0.22 Mu m filtered solution in PBS, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/µg as determined by LAL test. |
Target Information
| Gene Symbol | IL18RAP |
| Gene ID | 8807 |
| Uniprot ID | I18RA_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Phe20-Arg356 |
Additional Info
| Post Translational Modifications | N-glycosylated. |
| Function | Within the IL18 receptor complex, does not mediate IL18-binding, but involved in IL18-dependent signal transduction, leading to NF-kappa-B and JNK activation. May play a role in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells (Probable). |
| Protein Name | Interleukin-18 Receptor Accessory ProteinIl-18 Receptor Accessory ProteinIl-18racpAccessory Protein-LikeAcplCd218 Antigen-Like Family Member BCdw218bIl-1r Accessory Protein-LikeIl-1racplInterleukin-1 Receptor 7Il-1r-7Il-1r7Interleukin-18 Receptor Accessory Protein-LikeInterleukin-18 Receptor BetaIl-18r-BetaIl-18rbetaCd Antigen Cd218b |
| Database Links | Reactome: R-HSA-9012546 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Interleukin-18 Receptor Accessory Protein proteinIl-18 Receptor Accessory Protein proteinIl-18racp proteinAccessory Protein-Like proteinAcpl proteinCd218 Antigen-Like Family Member B proteinCdw218b proteinIl-1r Accessory Protein-Like proteinIl-1racpl proteinInterleukin-1 Receptor 7 proteinIl-1r-7 proteinIl-1r7 proteinInterleukin-18 Receptor Accessory Protein-Like proteinInterleukin-18 Receptor Beta proteinIl-18r-Beta proteinIl-18rbeta proteinCd Antigen Cd218b proteinIL18RAP proteinIL1R7 protein |
Information sourced from Uniprot.org