Human CD213a1/IL13RA1 protein (Recombinant-Active) (C-His) (STJP012046)
SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Active-Human CD213a1/IL13RA1-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | <0.1 EU/Mu g of the protein by the LAL method. |
| Immunoreactivity | Immobilised human IL-13 at 2 Mu g/ml (100 Mu l/well) on the plate. Dose response curve for Biotinylated human CD213a1/IL13RA1 with the EC50 of 2.8 Mu g/ml determined by ELISA. |
Target Information
| Gene Symbol | IL13RA1 |
| Gene ID | 3597 |
| Uniprot ID | I13R1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ala27-Thr343 |
Additional Info
| Function | Binds with low affinity to interleukin-13 (IL13). Together with IL4RA can form a functional receptor for IL13. Also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity. |
| Protein Name | Interleukin-13 Receptor Subunit Alpha-1Il-13 Receptor Subunit Alpha-1Il-13r Subunit Alpha-1Il-13r-Alpha-1Il-13ra1Cancer/Testis Antigen 19Ct19Cd Antigen Cd213a1 |
| Database Links | Reactome: R-HSA-6785807 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Interleukin-13 Receptor Subunit Alpha-1 proteinIl-13 Receptor Subunit Alpha-1 proteinIl-13r Subunit Alpha-1 proteinIl-13r-Alpha-1 proteinIl-13ra1 proteinCancer/Testis Antigen 19 proteinCt19 proteinCd Antigen Cd213a1 proteinIL13RA1 proteinIL13R proteinIL13RA protein |
Information sourced from Uniprot.org