Human CD16b/FCGR3B protein (Recombinant) (C-His) (STJP006997)

Name: Human CD16b/FCGR3B protein (Recombinant) (C-His) (STJP006997)
SKU: STJP006997
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostMammalian Cells

ImmunogenHomo sapiens (Human)

STJP006997

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Short Description	Recombinant-Human CD16b/FCGR3B-C-His protein was developed from mammalian cells for the region C-His. For use in research applications.
Applications	ELISA/Immunogen/SDS-PAGE/WB
Host	Mammalian Cells
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Dilution Range	Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Formulation	Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Post Translational Modifications	Glycosylated. Glycosylation plays an inhibitory role in the interaction with IgG3. The soluble form is produced by a proteolytic cleavage.
Function	Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
Protein Name	Low Affinity Immunoglobulin Gamma Fc Region Receptor Iii-B Fc-Gamma Riii-Beta Cd16-I Fc-Gamma Riii Fc-Gamma Riiib Fcriii Fcriiib Fcr-10 Igg Fc Receptor Iii-1 Cd Antigen Cd16b
Database Links	Reactome: R-HSA-163125 Reactome: R-HSA-6798695
Cellular Localisation	Cell Membrane Lipid-Anchor Gpi-Anchor Secreted Secreted After Cleavage
Alternative Protein Names	Low Affinity Immunoglobulin Gamma Fc Region Receptor Iii-B protein Fc-Gamma Riii-Beta protein Cd16-I protein Fc-Gamma Riii protein Fc-Gamma Riiib protein Fcriii protein Fcriiib protein Fcr-10 protein Igg Fc Receptor Iii-1 protein Cd Antigen Cd16b protein FCGR3B protein CD16B protein FCG3 protein FCGR3 protein IGFR3 protein

Information sourced from Uniprot.org