Human CD158k/KIR3DL2 protein (Recombinant) (C-Fc) (STJP006623)
SPECIFICATIONS
HostMammalian Cells
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CD158k/KIR3DL2-C-Fc protein was developed from mammalian cells for the region C-Fc. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | KIR3DL2 |
| Gene ID | 3812 |
| Uniprot ID | KI3L2_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-His338 |
Additional Info
| Function | Receptor on natural killer (NK) cells and T cells for MHC class I molecules. Upon binding of peptide-free HLA-F open conformer, negatively regulates NK and T cell effector functions. Acts as a receptor on astrocytes for HLA-F. Through interaction with HLA-F, may protect motor neurons from astrocyte-induced toxicity. |
| Protein Name | Killer Cell Immunoglobulin-Like Receptor 3dl2Cd158 Antigen-Like Family Member KNatural Killer-Associated Transcript 4Nkat-4P70 Natural Killer Cell Receptor Clone Cl-5P70 Nk Receptor Cl-5Cd Antigen Cd158k |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Killer Cell Immunoglobulin-Like Receptor 3dl2 proteinCd158 Antigen-Like Family Member K proteinNatural Killer-Associated Transcript 4 proteinNkat-4 proteinP70 Natural Killer Cell Receptor Clone Cl-5 proteinP70 Nk Receptor Cl-5 proteinCd Antigen Cd158k proteinKIR3DL2 proteinCD158K proteinNKAT4 protein |
Information sourced from Uniprot.org