Human CD137/TNFRSF9/4-1BB protein (Recombinant-Active) (C-Fc-His) (STJP012645)
SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Active-Human CD137/TNFRSF9/4-1BB-C-Fc-His protein was developed from mammalian cells and has a target region of C-Fc-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a 0.22 Mu m filtered solution in PBS, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8ยฐC for one week. Store at-20 to-80ยฐC for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/ยตg as determined by LAL test. |
Target Information
| Gene Symbol | TNFRSF9 |
| Gene ID | 3604 |
| Uniprot ID | TNR9_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Leu24-Gln186 |
Additional Info
| Function | Receptor for TNFSF9/4-1BBL. Conveys a signal that enhances CD8(+) T-cell survival, cytotoxicity, and mitochondrial activity, thereby promoting immunity against viruses and tumors (Probable). |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 94-1bb Ligand ReceptorCdw137T-Cell Antigen 4-1bb HomologT-Cell Antigen IlaCd Antigen Cd137 |
| Database Links | Reactome: R-HSA-5669034 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Tumor Necrosis Factor Receptor Superfamily Member 9 protein4-1bb Ligand Receptor proteinCdw137 proteinT-Cell Antigen 4-1bb Homolog proteinT-Cell Antigen Ila proteinCd Antigen Cd137 proteinTNFRSF9 proteinCD137 proteinILA protein |
Information sourced from Uniprot.org