Human CD114/CSF3R protein (Recombinant-Active) (C-His) (STJP012237)

Name: Human CD114/CSF3R protein (Recombinant-Active) (C-His) (STJP012237)
SKU: STJP012237-100
Price: 503.5 GBP
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostMammalian Cells

ConjugationUnconjugated

ImmunogenHomo sapiens (Human)

STJP012237-100

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Short Description	Recombinant-Active-Human CD114/CSF3R-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications.
Applications	ELISA/WB
Host	Mammalian Cells
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Conjugation	Unconjugated
Dilution Range	Reconstitute in sterile water for a stock solution.
Formulation	Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Storage Instruction	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin	<0.1 EU/Mu g of the protein by the LAL method.
Immunoreactivity	Measured by its ability to inhibit the G-CSF induced proliferation of mouse myelogenous leukemia lymphoblast cells (MNFS-60). The ED50 for this ettect is typically 31.5-126 ng/mL.

Post Translational Modifications	N-glycosylated.
Function	Receptor for granulocyte colony-stimulating factor (CSF3), essential for granulocytic maturation. Plays a crucial role in the proliferation, differentiation and survival of cells along the neutrophilic lineage. In addition it may function in some adhesion or recognition events at the cell surface.
Protein Name	Granulocyte Colony-Stimulating Factor Receptor G-Csf Receptor G-Csf-R Cd Antigen Cd114
Database Links	Reactome: R-HSA-449836 Reactome: R-HSA-9616222 Reactome: R-HSA-9674555 Reactome: R-HSA-9705462
Cellular Localisation	Isoform 2: Secreted Cell Membrane Single-Pass Type I Membrane Protein
Alternative Protein Names	Granulocyte Colony-Stimulating Factor Receptor protein G-Csf Receptor protein G-Csf-R protein Cd Antigen Cd114 protein CSF3R protein GCSFR protein

Information sourced from Uniprot.org