Human CD108/SEMA7A protein (Recombinant) (N-His) (STJP010570)

SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
STJP010570
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General Information

Short DescriptionRecombinant-Human CD108/SEMA7A-N-His protein was developed from e.coli for the region N-His. For use in research applications.
ApplicationsELISA/Immunogen/SDS-PAGE/WB
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Dilution RangeReconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
FormulationLyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Target Information

Gene SymbolSEMA7A
Gene ID8482
Uniprot IDSEM7A_HUMAN
ImmunogenHomo sapiens (Human)
Immunogen RegionAsp65-Thr399

Additional Info

Function Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of pro-inflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes.
Protein Name Semaphorin-7a
Cdw108
Jmh Blood Group Antigen
John-Milton-Hargen Human Blood Group Ag
Semaphorin-K1
Sema K1
Semaphorin-L
Sema L
Cd Antigen Cd108
Database Links Reactome: R-HSA-416700
Cellular Localisation Cell Membrane
Lipid-Anchor
Gpi-Anchor
Extracellular Side
Detected In A Punctate Pattern On The Cell Membrane Of Basal And Supra-Basal Skin Keratinocytes
Alternative Protein Names Semaphorin-7a protein
Cdw108 protein
Jmh Blood Group Antigen protein
John-Milton-Hargen Human Blood Group Ag protein
Semaphorin-K1 protein
Sema K1 protein
Semaphorin-L protein
Sema L protein
Cd Antigen Cd108 protein
SEMA7A protein
CD108 protein
SEMAL protein

Information sourced from Uniprot.org

Citations

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