Human CD108/SEMA7A protein (Recombinant) (N-His) (STJP010570)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CD108/SEMA7A-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | SEMA7A |
| Gene ID | 8482 |
| Uniprot ID | SEM7A_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Asp65-Thr399 |
Additional Info
| Function | Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of pro-inflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes. |
| Protein Name | Semaphorin-7aCdw108Jmh Blood Group AntigenJohn-Milton-Hargen Human Blood Group AgSemaphorin-K1Sema K1Semaphorin-LSema LCd Antigen Cd108 |
| Database Links | Reactome: R-HSA-416700 |
| Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorExtracellular SideDetected In A Punctate Pattern On The Cell Membrane Of Basal And Supra-Basal Skin Keratinocytes |
| Alternative Protein Names | Semaphorin-7a proteinCdw108 proteinJmh Blood Group Antigen proteinJohn-Milton-Hargen Human Blood Group Ag proteinSemaphorin-K1 proteinSema K1 proteinSemaphorin-L proteinSema L proteinCd Antigen Cd108 proteinSEMA7A proteinCD108 proteinSEMAL protein |
Information sourced from Uniprot.org