Human CD10/MME protein (Recombinant) (C-His) (STJP007021)

SPECIFICATIONS
HostMammalian Cells
ImmunogenHomo sapiens (Human)
STJP007021
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General Information

Short DescriptionRecombinant-Human CD10/MME-C-His protein was developed from mammalian cells for the region C-His. For use in research applications.
ApplicationsELISA/Immunogen/SDS-PAGE/WB
HostMammalian Cells
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Dilution RangeReconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
FormulationLyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Target Information

Gene SymbolMME
Gene ID4311
Uniprot IDNEP_HUMAN
ImmunogenHomo sapiens (Human)
Immunogen RegionTyr52-Trp750

Additional Info

Function Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Catalyzes cleavage of bradykinin, substance P and neurotensin peptides. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF) and brain natriuretic factor (BNP(1-32)). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers.
Protein Name Neprilysin
Atriopeptidase
Common Acute Lymphocytic Leukemia Antigen
Calla
Enkephalinase
Neutral Endopeptidase 24.11
Nep
Neutral Endopeptidase
Skin Fibroblast Elastase
Sfe
Cd Antigen Cd10
Database Links Reactome: R-HSA-2022377
Reactome: R-HSA-5578768
Reactome: R-HSA-6798695
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Alternative Protein Names Neprilysin protein
Atriopeptidase protein
Common Acute Lymphocytic Leukemia Antigen protein
Calla protein
Enkephalinase protein
Neutral Endopeptidase 24.11 protein
Nep protein
Neutral Endopeptidase protein
Skin Fibroblast Elastase protein
Sfe protein
Cd Antigen Cd10 protein
MME protein
EPN protein

Information sourced from Uniprot.org

Citations

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