Human CD-M6PR protein (Recombinant) (His-Tag) (STJP018771)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human CD-M6PR-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% Glycerol, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | M6PR |
| Gene ID | 4074 |
| Uniprot ID | MPRD_HUMAN |
| Accession Number | NP_002346 |
| Immunogen | Human |
| Immunogen Region | 27-185aa |
| Immunogen Sequence |
Additional Info
| Function | Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. |
| Protein Name | Cation-Dependent Mannose-6-Phosphate ReceptorCd Man-6-P ReceptorCd-Mpr46 Kda Mannose 6-Phosphate ReceptorMpr 46 |
| Database Links | Reactome: R-HSA-432720Reactome: R-HSA-6811440Reactome: R-HSA-8856825Reactome: R-HSA-8856828Reactome: R-HSA-9840310 |
| Cellular Localisation | Lysosome MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Cation-Dependent Mannose-6-Phosphate Receptor proteinCd Man-6-P Receptor proteinCd-Mpr protein46 Kda Mannose 6-Phosphate Receptor proteinMpr 46 proteinM6PR proteinMPR46 proteinMPRD protein |
Information sourced from Uniprot.org