Human CCS protein (Recombinant) (His-Tag) (STJP016855)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human CCS-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl 1mM DTT, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CCS |
| Gene ID | 9973 |
| Uniprot ID | CCS_HUMAN |
| Accession Number | NP_005116 |
| Immunogen | Human |
| Immunogen Region | 1-274aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Ubiquitous. |
| Post Translational Modifications | Ubiquitinion by XIAP/BIRC4 leads to enhancement of its chaperone activity toward its physiologic target, SOD1, rather than proteasomal degradation. XIAP/BIRC4 preferentially ubiquitinates at Lys-241. |
| Function | Delivers copper to copper zinc superoxide dismutase (SOD1). |
| Protein Name | Copper Chaperone For Superoxide DismutaseSuperoxide Dismutase Copper Chaperone |
| Database Links | Reactome: R-HSA-3299685 |
| Cellular Localisation | Cytoplasm |
| Alternative Protein Names | Copper Chaperone For Superoxide Dismutase proteinSuperoxide Dismutase Copper Chaperone proteinCCS protein |
Information sourced from Uniprot.org