Human CCL8/MCP-2 protein (Recombinant) (Tag free) (STJP014584)
SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CCL8/MCP-2-Tag free protein was developed from e.coli and has a target region of Tag free. For use in research applications. |
| Applications | ELISA/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a 0.22 Mu m filtered solution in 20mM PB, 150mM NaCl, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/µg as determined by LAL test. |
Target Information
| Gene Symbol | CCL8 |
| Gene ID | 6355 |
| Uniprot ID | CCL8_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Gln24-Pro99 |
Additional Info
| Post Translational Modifications | N-terminal processed form MCP-2(6-76) is produced by proteolytic cleavage after secretion from peripheral blood monocytes. |
| Function | Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. May play a role in neoplasia and inflammatory host responses. This protein can bind heparin. The processed form MCP-2(6-76) does not show monocyte chemotactic activity, but inhibits the chemotactic effect most predominantly of CCL7, and also of CCL2 and CCL5 and CCL8. |
| Protein Name | C-C Motif Chemokine 8Hc14Monocyte Chemoattractant Protein 2Monocyte Chemotactic Protein 2Mcp-2Small-Inducible Cytokine A8 Cleaved Into - Mcp-2(6-76 |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Protein Names | C-C Motif Chemokine 8 proteinHc14 proteinMonocyte Chemoattractant Protein 2 proteinMonocyte Chemotactic Protein 2 proteinMcp-2 proteinSmall-Inducible Cytokine A8 Cleaved Into - Mcp-2(6-76 proteinCCL8 proteinMCP2 proteinSCYA10 proteinSCYA8 protein |
Information sourced from Uniprot.org