Human CCL7/MCP-3 protein (Recombinant) (No tag) (STJP000839)
SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenRecombinant Human CCL7/MCP-3 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Gln24-Leu99) of human MCP-3/CCL7 (Accession #NP_006264.2).
General Information
| Short Description | Recombinant-Human CCL7/MCP-3-No tag protein was developed in e.coli using the region Gln24-Leu99. For use in research applications. |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of 20mM Tris, 500mM NaCl, pH 8.0. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | < 1.0 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | CCL7 |
| Gene ID | 6354 |
| Uniprot ID | CCL7_HUMAN |
| Immunogen | Recombinant Human CCL7/MCP-3 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Gln24-Leu99) of human MCP-3/CCL7 (Accession #NP_006264.2). |
| Immunogen Region | Gln24-Leu99 |
| Immunogen Sequence | QPVGINTSTTCCYRFINKKI PKQRLESYRRTTSSHCPREA VIFKTKLDKEICADPTQKWV QDFMKHLDKKTQTPKL |
Additional Info
| Post Translational Modifications | O-glycosylated. |
| Function | Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3. |
| Protein Name | C-C Motif Chemokine 7Monocyte Chemoattractant Protein 3Monocyte Chemotactic Protein 3Mcp-3Nc28Small-Inducible Cytokine A7 |
| Database Links | Reactome: R-HSA-380108 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | C-C Motif Chemokine 7 proteinMonocyte Chemoattractant Protein 3 proteinMonocyte Chemotactic Protein 3 proteinMcp-3 proteinNc28 proteinSmall-Inducible Cytokine A7 proteinCCL7 proteinMCP3 proteinSCYA6 proteinSCYA7 protein |
Information sourced from Uniprot.org