Human CCL3L1/LD78-beta protein (Recombinant) (His-Tag) (STJP017053)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human CCL3L1/LD78-beta-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.25 mg/mL |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Endotoxin | < 1 EU per 1ug of protein (determined by LAL method) |
Target Information
| Gene Symbol | CCL3L1.CCL3L3 |
| Gene ID | 414062/6349 |
| Uniprot ID | CL3L1_HUMAN |
| Accession Number | NP_066286 |
| Immunogen | Human |
| Immunogen Region | 26-93aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MSLAADTPTA CCFSYTSRQI PQNFIADYFE TSSQCSKPSV IFLTKRGRQV CADPSEEWVQ KYVSDLELSA |
Additional Info
| Post Translational Modifications | The N-terminal processed forms LD78-beta(3-70) and LD78-beta(5-70) are produced by proteolytic cleavage after secretion from peripheral blood monocytes. The cleavage to yield LD78-beta(3-70) is probably achieved by DPP4. |
| Function | Chemotactic for lymphocytes and monocytes. Is a ligand for CCR1, CCR3 and CCR5. Is an inhibitor of HIV-1-infection. The processed form LD78-beta(3-70) shows a 20-fold to 30-fold higher chemotactic activity and is a very potent inhibitor of HIV-1-infection. LD78-beta(3-70) is also a ligand for CCR1, CCR3 and CCR5. |
| Protein Name | C-C Motif Chemokine 3-Like 1G0/G1 Switch Regulatory Protein 19-2Ld78-Beta(1-70Pat 464.2Small-Inducible Cytokine A3-Like 1Tonsillar Lymphocyte Ld78 Beta Protein Cleaved Into - Ld78-Beta(3-70 - Ld78-Beta(5-70 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-6783783 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | C-C Motif Chemokine 3-Like 1 proteinG0/G1 Switch Regulatory Protein 19-2 proteinLd78-Beta(1-70 proteinPat 464.2 proteinSmall-Inducible Cytokine A3-Like 1 proteinTonsillar Lymphocyte Ld78 Beta Protein Cleaved Into - Ld78-Beta(3-70 - Ld78-Beta(5-70 proteinCCL3L1 proteinD17S1718 proteinG0S19-2 proteinSCYA3L1.CCL3L3 protein |
Information sourced from Uniprot.org