Human CCL3/MIP-1 alpha protein (Recombinant) (His-Tag) (STJP017155)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human CCL3/MIP-1 alpha-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.25 mg/mL |
| Formulation | Liquid in 10mM Sodium Citrate buffer (pH 3.5) containing 20% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Endotoxin | < 1 EU per 1ug of protein (determined by LAL method) |
Target Information
| Gene Symbol | CCL3 |
| Gene ID | 6348 |
| Uniprot ID | CCL3_HUMAN |
| Accession Number | NP_002974.1 |
| Immunogen | Human |
| Immunogen Region | 24-92aa |
| Immunogen Sequence |
Additional Info
| Post Translational Modifications | N-terminal processed form LD78-alpha(4-69) is produced by proteolytic cleavage after secretion from HTLV1-transformed T-cells. |
| Function | Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). |
| Protein Name | C-C Motif Chemokine 3G0/G1 Switch Regulatory Protein 19-1Macrophage Inflammatory Protein 1-AlphaMip-1-AlphaPat 464.1Sis-BetaSmall-Inducible Cytokine A3Tonsillar Lymphocyte Ld78 Alpha Protein Cleaved Into - Mip-1-Alpha(4-69Ld78-Alpha(4-69 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-6783783 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | C-C Motif Chemokine 3 proteinG0/G1 Switch Regulatory Protein 19-1 proteinMacrophage Inflammatory Protein 1-Alpha proteinMip-1-Alpha proteinPat 464.1 proteinSis-Beta proteinSmall-Inducible Cytokine A3 proteinTonsillar Lymphocyte Ld78 Alpha Protein Cleaved Into - Mip-1-Alpha(4-69 proteinLd78-Alpha(4-69 proteinCCL3 proteinG0S19-1 proteinMIP1A proteinSCYA3 protein |
Information sourced from Uniprot.org