Human CCL22/MDC protein (Recombinant) (N-GST) (STJP003169)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CCL22/MDC-N-GST protein was developed from e.coli for the region N-GST. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | CCL22 |
| Gene ID | 6367 |
| Uniprot ID | CCL22_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Gly25-Gln93 |
Additional Info
| Post Translational Modifications | The N-terminal processed forms MDC(3-69), MDC(5-69) and MDC(7-69) are produced by proteolytic cleavage after secretion from monocyte derived dendrocytes. |
| Function | May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Chemotactic for monocytes, dendritic cells and natural killer cells. Mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemoattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4. Processed forms MDC(3-69), MDC(5-69) and MDC(7-69) seem not be active. |
| Protein Name | C-C Motif Chemokine 22Cc Chemokine Stcp-1Mdc(1-69Macrophage-Derived ChemokineSmall-Inducible Cytokine A22Stimulated T-Cell Chemotactic Protein 1 Cleaved Into - Mdc(3-69 - Mdc(5-69 - Mdc(7-69 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-6783783Reactome: R-HSA-6785807 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | C-C Motif Chemokine 22 proteinCc Chemokine Stcp-1 proteinMdc(1-69 proteinMacrophage-Derived Chemokine proteinSmall-Inducible Cytokine A22 proteinStimulated T-Cell Chemotactic Protein 1 Cleaved Into - Mdc(3-69 - Mdc(5-69 - Mdc(7-69 proteinCCL22 proteinMDC proteinSCYA22 proteinA-152E5.1 protein |
Information sourced from Uniprot.org