Human CCL21 protein (Recombinant) (No tag) (STJP001396)
SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenRecombinant Human CCL21 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Ser24-Pro134) of human CCL21/6Ckine (Accession #NP_002980.1) fused with no additional amino acid.
General Information
| Short Description | Recombinant-Human CCL21-No tag protein was developed in e.coli using the region Ser24-Pro134. For use in research applications. |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | Please contact us for more information. |
Target Information
| Gene Symbol | CCL21 |
| Gene ID | 6366 |
| Uniprot ID | CCL21_HUMAN |
| Immunogen | Recombinant Human CCL21 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Ser24-Pro134) of human CCL21/6Ckine (Accession #NP_002980.1) fused with no additional amino acid. |
| Immunogen Region | Ser24-Pro134 |
| Immunogen Sequence | SDGGAQDCCLKYSQRKIPAK VVRSYRKQEPSLGCSIPAIL FLPRKRSQAELCADPKELWV QQLMQHLDKTPSPQKPAQGC RKDRGASKTGKKGKGSKGCK RTERSQTPKGP |
Additional Info
| Function | Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. |
| Protein Name | C-C Motif Chemokine 216ckineBeta-Chemokine Exodus-2Secondary Lymphoid-Tissue ChemokineSlcSmall-Inducible Cytokine A21 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | C-C Motif Chemokine 21 protein6ckine proteinBeta-Chemokine Exodus-2 proteinSecondary Lymphoid-Tissue Chemokine proteinSlc proteinSmall-Inducible Cytokine A21 proteinCCL21 proteinSCYA21 proteinUNQ784 proteinPRO1600 protein |
Information sourced from Uniprot.org