• Human CCL19/MIP-3 beta protein (Recombinant) (C-His) (STJP001992)

Human CCL19/MIP-3 beta protein (Recombinant) (C-His) (STJP001992)

SKU:
STJP001992

$154.58 - $663.53
Current Stock:
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human CCL19/MIP-3 beta-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CCL19
Gene ID: 6363
Uniprot ID: CCL19_HUMAN
Immunogen Region: Gly22-Ser98
Immunogen: Recombinant Human CCL19/MIP-3 beta Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Gly22-Ser98) of human CCL19/MIP-3 beta (Accession #NP_006265.1) fused with a 6×His tag at the C-terminus.
Function May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
Protein Name C-C Motif Chemokine 19
Beta-Chemokine Exodus-3
Ck Beta-11
Epstein-Barr Virus-Induced Molecule 1 Ligand Chemokine
Ebi1 Ligand Chemokine
Elc
Macrophage Inflammatory Protein 3 Beta
Mip-3-Beta
Small-Inducible Cytokine A19
Database Links Reactome: R-HSA-380108
Reactome: R-HSA-418594
Reactome: R-HSA-6783783
Cellular Localisation Secreted
Alternative Protein Names C-C Motif Chemokine 19 protein
Beta-Chemokine Exodus-3 protein
Ck Beta-11 protein
Epstein-Barr Virus-Induced Molecule 1 Ligand Chemokine protein
Ebi1 Ligand Chemokine protein
Elc protein
Macrophage Inflammatory Protein 3 Beta protein
Mip-3-Beta protein
Small-Inducible Cytokine A19 protein
CCL19 protein
ELC protein
MIP3B protein
SCYA19 protein

Information sourced from Uniprot.org

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