Post Translational Modifications | The Cys-30/Cys-54 disulfide bond is required for activity. |
Function | Chemotactic factor that attracts lymphocytes but not monocytes or granulocytes. May be involved in B-cell migration into B-cell follicles in lymph nodes. Attracts naive T-lymphocytes toward dendritic cells and activated macrophages in lymph nodes, has chemotactic activity for naive T-cells, CD4+ and CD8+ T-cells and thus may play a role in both humoral and cell-mediated immunity responses. |
Protein Name | C-C Motif Chemokine 18Alternative Macrophage Activation-Associated Cc Chemokine 1Amac-1Cc Chemokine ParcDendritic Cell Chemokine 1Dc-Ck1Macrophage Inflammatory Protein 4Mip-4Pulmonary And Activation-Regulated ChemokineSmall-Inducible Cytokine A18 Cleaved Into - Ccl18(1-68 - Ccl18(3-69 - Ccl18(4-69 |
Cellular Localisation | Secreted |
Alternative Protein Names | C-C Motif Chemokine 18 proteinAlternative Macrophage Activation-Associated Cc Chemokine 1 proteinAmac-1 proteinCc Chemokine Parc proteinDendritic Cell Chemokine 1 proteinDc-Ck1 proteinMacrophage Inflammatory Protein 4 proteinMip-4 proteinPulmonary And Activation-Regulated Chemokine proteinSmall-Inducible Cytokine A18 Cleaved Into - Ccl18(1-68 - Ccl18(3-69 - Ccl18(4-69 proteinCCL18 proteinAMAC1 proteinDCCK1 proteinMIP4 proteinPARC proteinSCYA18 protein |
Information sourced from Uniprot.org