Human CCL18 (CCL18) Antibody Pair (STJAP00705)
General Information
| Short Description | This CCL18 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the. |
| Applications | ELISA |
| Host | Rabbit/Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal/Monoclonal |
| Clone ID | R05-6B4/R01-7B4 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | Determined by end user |
| Formulation | 0.01M PBS, pH 7.2 |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | CCL18 |
| Gene ID | 6362 |
| Uniprot ID | CCL18_HUMAN |
| Immunogen | Recombinant protein of human CCL18 |
Additional Info
| Tissue Specificity | Expressed at high levels in lung, lymph nodes, placenta, bone marrow, dendritic cells present in germinal centers and T-cell areas of secondary lymphoid organs and macrophages derived from peripheral blood monocytes. Not expressed by peripheral blood monocytes and a monocyte-to-macrophage differentiation is a prerequisite for expression. Expressed in synovial fluids from patients with rheumatoid and septic arthritis and in ovarian carcinoma ascitic fluid. |
| Post Translational Modifications | The Cys-30/Cys-54 disulfide bond is required for activity. |
| Function | Chemotactic factor that attracts lymphocytes but not monocytes or granulocytes. May be involved in B-cell migration into B-cell follicles in lymph nodes. Attracts naive T-lymphocytes toward dendritic cells and activated macrophages in lymph nodes, has chemotactic activity for naive T-cells, CD4+ and CD8+ T-cells and thus may play a role in both humoral and cell-mediated immunity responses. |
| Protein Name | C-C Motif Chemokine 18Alternative Macrophage Activation-Associated Cc Chemokine 1Amac-1Cc Chemokine ParcDendritic Cell Chemokine 1Dc-Ck1Macrophage Inflammatory Protein 4Mip-4Pulmonary And Activation-Regulated ChemokineSmall-Inducible Cytokine A18 Cleaved Into - Ccl18(1-68 - Ccl18(3-69 - Ccl18(4-69 |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Antibody Pair Names | C-C Motif Chemokine 18 antibody pairAlternative Macrophage Activation-Associated Cc Chemokine 1 antibody pairAmac-1 antibody pairCc Chemokine Parc antibody pairDendritic Cell Chemokine 1 antibody pairDc-Ck1 antibody pairMacrophage Inflammatory Protein 4 antibody pairMip-4 antibody pairPulmonary And Activation-Regulated Chemokine antibody pairSmall-Inducible Cytokine A18 Cleaved Into - Ccl18(1-68 - Ccl18(3-69 - Ccl18(4-69 antibody pairCCL18 antibody pairAMAC1 antibody pairDCCK1 antibody pairMIP4 antibody pairPARC antibody pairSCYA18 antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human CCL18 (CCL18) Antibody Pair (STJAP00705)
This antibody pair detects human CCL18 (UniProt P55774) and is validated for human reactivity only. Both antibodies were raised against a recombinant protein of human CCL18.
Both antibodies are rabbit monoclonal IgGs supplied unconjugated at 1 mg/mL, formulated in 0.01M PBS at pH 7.2, and affinity purified. The clone IDs are R05-6B4 and R01-7B4 respectively.
This pair is validated for use in ELISA. No other assay formats are listed for this product.
Optimal working dilutions are determined by the end user and are not predefined in the product specifications. Titration is recommended to establish the appropriate concentrations for each antibody in the intended assay setup.
Both antibodies should be stored at 4°C for short-term use. For long-term storage, aliquots should be kept at -20°C, and repeated freeze/thaw cycles should be avoided to maintain activity.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.