Human CCL18 (CCL18) Antibody Pair (STJAP00705)
SPECIFICATIONS
ClonalityMonoclonal/Monoclonal
HostRabbit/Rabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein of human CCL18
General Information
| Short Description | This CCL18 antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the. |
| Applications | ELISA |
| Host | Rabbit/Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal/Monoclonal |
| Clone ID | R05-6B4/R01-7B4 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | Determined by end user |
| Formulation | 0.01M PBS, pH 7.2 |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | CCL18 |
| Gene ID | 6362 |
| Uniprot ID | CCL18_HUMAN |
| Immunogen | Recombinant protein of human CCL18 |
Additional Info
| Tissue Specificity | Expressed at high levels in lung, lymph nodes, placenta, bone marrow, dendritic cells present in germinal centers and T-cell areas of secondary lymphoid organs and macrophages derived from peripheral blood monocytes. Not expressed by peripheral blood monocytes and a monocyte-to-macrophage differentiation is a prerequisite for expression. Expressed in synovial fluids from patients with rheumatoid and septic arthritis and in ovarian carcinoma ascitic fluid. |
| Post Translational Modifications | The Cys-30/Cys-54 disulfide bond is required for activity. |
| Function | Chemotactic factor that attracts lymphocytes but not monocytes or granulocytes. May be involved in B-cell migration into B-cell follicles in lymph nodes. Attracts naive T-lymphocytes toward dendritic cells and activated macrophages in lymph nodes, has chemotactic activity for naive T-cells, CD4+ and CD8+ T-cells and thus may play a role in both humoral and cell-mediated immunity responses. |
| Protein Name | C-C Motif Chemokine 18Alternative Macrophage Activation-Associated Cc Chemokine 1Amac-1Cc Chemokine ParcDendritic Cell Chemokine 1Dc-Ck1Macrophage Inflammatory Protein 4Mip-4Pulmonary And Activation-Regulated ChemokineSmall-Inducible Cytokine A18 Cleaved Into - Ccl18(1-68 - Ccl18(3-69 - Ccl18(4-69 |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Antibody Pair Names | C-C Motif Chemokine 18 antibody pairAlternative Macrophage Activation-Associated Cc Chemokine 1 antibody pairAmac-1 antibody pairCc Chemokine Parc antibody pairDendritic Cell Chemokine 1 antibody pairDc-Ck1 antibody pairMacrophage Inflammatory Protein 4 antibody pairMip-4 antibody pairPulmonary And Activation-Regulated Chemokine antibody pairSmall-Inducible Cytokine A18 Cleaved Into - Ccl18(1-68 - Ccl18(3-69 - Ccl18(4-69 antibody pairCCL18 antibody pairAMAC1 antibody pairDCCK1 antibody pairMIP4 antibody pairPARC antibody pairSCYA18 antibody pair |
Information sourced from Uniprot.org