Human CCL15/MIP-1 delta protein (Recombinant) (No-Tag) (STJP017148)

Name: Human CCL15/MIP-1 delta protein (Recombinant) (No-Tag) (STJP017148)
SKU: STJP017148
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostE.coli

ImmunogenHuman

STJP017148

Current Stock:

🚚 Free UK Delivery on orders over £150

Quantity:

Processing The item has been added

Enquire For Bulk Order

✓ 1-Year Performance Guarantee | SDS & Datasheet Included | Expert Tech Support | Covered by St John's Laboratory Guarantee

Short Description	Recombinant-Human CCL15/MIP-1 delta-No-Tag protein was developed from e.coli and has a target region of No-Tag. For use in research applications.
Applications	SDS-PAGE
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration	0.5 mg/mL
Formulation	Liquid in phosphate-Buffered Saline (pH 7.4) 10% Glycerol
Storage Instruction	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Endotoxin	< 1 EU per 1ug of protein (determined by LAL method)

Gene Symbol	CCL15
Gene ID	6359
Uniprot ID	CCL15_HUMAN
Accession Number	NP_116741
Immunogen	Human
Immunogen Region	22-113aa
Immunogen Sequence	MQFINDAETE LMMSKLPLEN PVVLNSFHFA ADCCTSYISQ SIPCSLMKSY FETSSECSKP GVIFLTKKGR QVCAKPSGPG VQDCMKKLKP YSI

Tissue Specificity	Most abundant in heart, skeletal muscle and adrenal gland. Lower levels in placenta, liver, pancreas and bone marrow. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are found in high levels in synovial fluids from rheumatoid patients.
Post Translational Modifications	The N-terminal is proteolytically cleaved by proteases associated with inflammatory responses. The processed forms CCL15(22-92), CCL15(25-92) and CCL15(29-92) exhibit increase in CCR1-mediated signaling and chemotaxis assays in vitro.
Function	Chemotactic factor that attracts T-cells and monocytes, but not neutrophils, eosinophils, or B-cells. Acts mainly via CC chemokine receptor CCR1. Also binds to CCR3. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are more potent chemoattractants than the CCL15.
Protein Name	C-C Motif Chemokine 15 Chemokine Cc-2 Hcc-2 Leukotactin-1 Lkn-1 Mip-1 Delta Macrophage Inflammatory Protein 5 Mip-5 Mrp-2b Ncc-3 Small-Inducible Cytokine A15 Cleaved Into - Ccl15(22-92 - Ccl15(25-92 - Ccl15(29-92
Database Links
Cellular Localisation	Secreted
Alternative Protein Names	C-C Motif Chemokine 15 protein Chemokine Cc-2 protein Hcc-2 protein Leukotactin-1 protein Lkn-1 protein Mip-1 Delta protein Macrophage Inflammatory Protein 5 protein Mip-5 protein Mrp-2b protein Ncc-3 protein Small-Inducible Cytokine A15 Cleaved Into - Ccl15(22-92 - Ccl15(25-92 - Ccl15(29-92 protein CCL15 protein MIP5 protein NCC3 protein SCYA15 protein

Information sourced from Uniprot.org