Human CCL15/HCC-2/LKN-1/MIP-5 protein (Recombinant) (N-GST) (STJP005508)

Name: Human CCL15/HCC-2/LKN-1/MIP-5 protein (Recombinant) (N-GST) (STJP005508)
SKU: STJP005508
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostE.coli

ImmunogenHomo sapiens (Human)

STJP005508

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Short Description	Recombinant-Human CCL15/HCC-2/LKN-1/MIP-5-N-GST protein was developed from e.coli for the region N-GST. For use in research applications.
Applications	ELISA/Immunogen/SDS-PAGE/WB
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Dilution Range	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Formulation	Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage Instruction	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Post Translational Modifications	The N-terminal is proteolytically cleaved by proteases associated with inflammatory responses. The processed forms CCL15(22-92), CCL15(25-92) and CCL15(29-92) exhibit increase in CCR1-mediated signaling and chemotaxis assays in vitro.
Function	Chemotactic factor that attracts T-cells and monocytes, but not neutrophils, eosinophils, or B-cells. Acts mainly via CC chemokine receptor CCR1. Also binds to CCR3. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are more potent chemoattractants than the CCL15.
Protein Name	C-C Motif Chemokine 15 Chemokine Cc-2 Hcc-2 Leukotactin-1 Lkn-1 Mip-1 Delta Macrophage Inflammatory Protein 5 Mip-5 Mrp-2b Ncc-3 Small-Inducible Cytokine A15 Cleaved Into - Ccl15(22-92 - Ccl15(25-92 - Ccl15(29-92
Database Links
Cellular Localisation	Secreted
Alternative Protein Names	C-C Motif Chemokine 15 protein Chemokine Cc-2 protein Hcc-2 protein Leukotactin-1 protein Lkn-1 protein Mip-1 Delta protein Macrophage Inflammatory Protein 5 protein Mip-5 protein Mrp-2b protein Ncc-3 protein Small-Inducible Cytokine A15 Cleaved Into - Ccl15(22-92 - Ccl15(25-92 - Ccl15(29-92 protein CCL15 protein MIP5 protein NCC3 protein SCYA15 protein

Information sourced from Uniprot.org