Human CCL13/MCP-4 protein (Recombinant) (N-GST) (STJP005896)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CCL13/MCP-4-N-GST protein was developed from e.coli for the region N-GST. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | CCL13 |
| Gene ID | 6357 |
| Uniprot ID | CCL13_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Gln24-Thr98 |
Additional Info
| Post Translational Modifications | One major form (form long), and two minor forms (short chain and medium chain) are produced by differential signal peptide cleavage. The medium chain is about 30-fold less active than the long chain. |
| Function | Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils, but not neutrophils. Signals through CCR2B and CCR3 receptors. Plays a role in the accumulation of leukocytes at both sides of allergic and non-allergic inflammation. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. May play a role in the monocyte attraction in tissues chronically exposed to exogenous pathogens. |
| Protein Name | C-C Motif Chemokine 13Ck-Beta-10Monocyte Chemoattractant Protein 4Monocyte Chemotactic Protein 4Mcp-4Ncc-1Small-Inducible Cytokine A13 Cleaved Into - C-C Motif Chemokine 13 - Long Chain - C-C Motif Chemokine 13 - Medium Chain - C-C Motif Chemokine 13 - Short Chain |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | C-C Motif Chemokine 13 proteinCk-Beta-10 proteinMonocyte Chemoattractant Protein 4 proteinMonocyte Chemotactic Protein 4 proteinMcp-4 proteinNcc-1 proteinSmall-Inducible Cytokine A13 Cleaved Into - C-C Motif Chemokine 13 - Long Chain - C-C Motif Chemokine 13 - Medium Chain - C-C Motif Chemokine 13 - Short Chain proteinCCL13 proteinMCP4 proteinNCC1 proteinSCYA13 protein |
Information sourced from Uniprot.org