Human CCL11/Eotaxin-1 protein (Recombinant) (His-Tag) (STJP016589)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human CCL11/Eotaxin-1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol, 1mM DTT, 0.1 M NaCl. |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Endotoxin | < 1 EU per 1ug of protein (determined by LAL method) |
Target Information
| Gene Symbol | CCL11 |
| Gene ID | 6356 |
| Uniprot ID | CCL11_HUMAN |
| Accession Number | NP_002977 |
| Immunogen | Human |
| Immunogen Region | 24-97aa |
| Immunogen Sequence |
Additional Info
| Post Translational Modifications | O-linked glycan consists of a Gal-GalNAc disaccharide which is modified with up to 2 sialic acid residues. |
| Function | In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3. |
| Protein Name | EotaxinC-C Motif Chemokine 11Eosinophil Chemotactic ProteinSmall-Inducible Cytokine A11 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-6785807 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Eotaxin proteinC-C Motif Chemokine 11 proteinEosinophil Chemotactic Protein proteinSmall-Inducible Cytokine A11 proteinCCL11 proteinSCYA11 protein |
Information sourced from Uniprot.org