| Short Description : | Recombinant-Human CCDC69-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications: | SDS-PAGE |
| Host: | E.coli |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Concentration: | 0.25 mg/mL |
| Formulation: | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% Glycerol, 1mM DTT |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CCDC69 |
| Gene ID: | 26112 |
| Uniprot ID: | CCD69_HUMAN |
| Accession Number: | NP_056436 |
| Immunogen: | Human |
| Immunogen Region: | 1-296aa |
| Immunogen Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMGCRHSR LSSCKPPKKK RQEPEPEQPP RPEPHELGPL NGDTAITVQL CASEEAERHQ KDITRILQQH EEEKKKWAQQ VEKERELELR DRLDEQQRVL EGKNEEALQV LRASYEQEKE ALTHSFREAS STQQETIDRL TSQLEAFQAK MKRVEESILS RNYKKHIQDY GSPSQFWEQE LESLHFVIEM KNERIHELDR RLILMETV |
| Tissue Specificity | Highly expressed in duodenum, esophagus, pancreas, prostate, salivary gland, thymus and urinary bladder. |
| Function | May act as a scaffold to regulate the recruitment and assembly of spindle midzone components. Required for the localization of AURKB and PLK1 to the spindle midzone. |
| Protein Name | Coiled-Coil Domain-Containing Protein 69 |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonSpindleMidbodyDuring Early AnaphaseLocalizes Along Overlapping Interpolar Microtubules Between The Separating ChromosomesDuring Late AnaphaseLocalizes To The Center Of Spindle MidzoneConcentrated At The Midbody During Telophase |
| Alternative Protein Names | Coiled-Coil Domain-Containing Protein 69 proteinCCDC69 protein |
Information sourced from Uniprot.org
