Human CBX1 protein (Recombinant) (N-His) (STJP007765)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CBX1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | CBX1 |
| Gene ID | 10951 |
| Uniprot ID | CBX1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Glu24-Leu168 |
Additional Info
| Post Translational Modifications | Not phosphorylated. Ubiquitinated. |
| Function | Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane. |
| Protein Name | Chromobox Protein Homolog 1Hp1hsbetaHeterochromatin Protein 1 Homolog BetaHp1 BetaHeterochromatin Protein P25M31Modifier 1 ProteinP25beta |
| Database Links | Reactome: R-HSA-9609690 |
| Cellular Localisation | NucleusUnassociated With Chromosomes During Mitosis |
| Alternative Protein Names | Chromobox Protein Homolog 1 proteinHp1hsbeta proteinHeterochromatin Protein 1 Homolog Beta proteinHp1 Beta proteinHeterochromatin Protein P25 proteinM31 proteinModifier 1 Protein proteinP25beta proteinCBX1 proteinCBX protein |
Information sourced from Uniprot.org