Human CBX1 protein (Recombinant) (His-Tag) (STJP017248)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human CBX1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 20% Glycerol, 2mM DTT, 0.1M NaCl. |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CBX1 |
| Gene ID | 10951 |
| Uniprot ID | CBX1_HUMAN |
| Accession Number | NP_006798 |
| Immunogen | Human |
| Immunogen Region | 1-185aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MGKKQNKKKV EEVLEEEEEE YVVEKVLDRR VVKGKVEYLL KWKGFSDEDN TWEPEENLDC PDLIAEFLQS QKTAHETDKS EGGKRKADSD SEDKGEESKP KKKKEESEKP RGFARGLEPE RIIGATDSSG ELMFLMKWKN SDEADLVPAK EANVKCPQVV ISFYEERLTW HSYPSEDDDK KDDKN |
Additional Info
| Tissue Specificity | Expressed in all adult and embryonic tissues. |
| Post Translational Modifications | Not phosphorylated. Ubiquitinated. |
| Function | Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane. |
| Protein Name | Chromobox Protein Homolog 1Hp1hsbetaHeterochromatin Protein 1 Homolog BetaHp1 BetaHeterochromatin Protein P25M31Modifier 1 ProteinP25beta |
| Database Links | Reactome: R-HSA-9609690 |
| Cellular Localisation | NucleusUnassociated With Chromosomes During Mitosis |
| Alternative Protein Names | Chromobox Protein Homolog 1 proteinHp1hsbeta proteinHeterochromatin Protein 1 Homolog Beta proteinHp1 Beta proteinHeterochromatin Protein P25 proteinM31 proteinModifier 1 Protein proteinP25beta proteinCBX1 proteinCBX protein |
Information sourced from Uniprot.org