Human Carnosinase protein (Recombinant) (STJP000673)
SPECIFICATIONS
HostHEK293
ConjugationUnconjugated
ImmunogenOptimized DNA sequence encodingHuman Carnosinase-CNDP1 (SER28-HIS508) mature chain including a C-terminal His tag was expressed in HEK293 cells. NA
General Information
| Short Description | Recombinant-Human Carnosinase-protein was developed from hek293. For use in research applications. |
| Host | HEK293 |
| Note | STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers. |
| Formulation | Lyophilised from 0.2 Mu m filtered PBS solution, pH7.2, 5% Trehalose. |
| Storage Instruction | Can be stored in working aliquots at 2°C-8°C C for one month, or at-20°C to-70°C for 1 year. Avoid repeated freeze/thaw cycles. NA |
| Endotoxin | Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg (1EU/µg). NA |
| Immunoreactivity | The activity was measured by the ability to cleave carnosine, the activity was calculated to be >250 pmol/min/?g NA |
Target Information
| Gene Symbol | CNDP1 |
| Gene ID | 84735 |
| Uniprot ID | CNDP1_HUMAN |
| Immunogen | Optimized DNA sequence encodingHuman Carnosinase-CNDP1 (SER28-HIS508) mature chain including a C-terminal His tag was expressed in HEK293 cells. NA |
| Immunogen Region | Mature chain |
Additional Info
| Tissue Specificity | Found in serum and adult nervous central system. Absent in serum from patients with homocarnosinosis. |
| Function | Catalyzes the peptide bond hydrolysis in Xaa-His dipeptides, displaying the highest activity toward carnosine (beta-alanyl-L-histidine) and anserine (beta-alanyl-3-methyl-histidine). |
| Protein Name | Beta-Ala-His DipeptidaseCndp Dipeptidase 1Carnosine Dipeptidase 1Glutamate Carboxypeptidase-Like Protein 2Serum Carnosinase |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Beta-Ala-His Dipeptidase proteinCndp Dipeptidase 1 proteinCarnosine Dipeptidase 1 proteinGlutamate Carboxypeptidase-Like Protein 2 proteinSerum Carnosinase proteinCNDP1 proteinCN1 proteinCPGL2 proteinUNQ1915 proteinPRO4380 protein |
Information sourced from Uniprot.org