Human CARD18 protein (Recombinant) (His-Tag) (STJP017583)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human CARD18-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% Glycerol, 0.1M NaCl |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CARD18 |
| Gene ID | 59082 |
| Uniprot ID | CAR18_HUMAN |
| Accession Number | NP_067546 |
| Immunogen | Human |
| Immunogen Region | 1-90aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MADQLLRKKR RIFIHSVGAG TINALLDCLL EDEVISQEDM NKVRDENDTV MDKARVLIDL VTGKGPKSCC KFIKHLCEED PQLASKMGLH |
Additional Info
| Tissue Specificity | Primarily expressed in the heart and placenta. |
| Function | Inhibits generation of IL-1-beta by interacting with caspase-1 and preventing its association with RIP2. Down-regulates the release of IL1B. |
| Protein Name | Caspase Recruitment Domain-Containing Protein 18Caspase-1 Inhibitor Iceberg |
| Database Links | |
| Cellular Localisation | |
| Alternative Protein Names | Caspase Recruitment Domain-Containing Protein 18 proteinCaspase-1 Inhibitor Iceberg proteinCARD18 proteinICEBERG proteinUNQ5804 proteinPRO19611 protein |
Information sourced from Uniprot.org