Human Carbonic Anhydrase 14/CA14 protein (Recombinant) (His-Tag) (STJP018585)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human Carbonic Anhydrase 14/CA14-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Enzyme Activity |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% Glycerol, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity | Specific activity is > 700pmol/min/ug, and is defined as the amount of enzyme that hydrolyze 1.0pmole of 4-nitrophenyl acetate to 4-nitrophenol per minute at pH 7.5 at 37C. |
Target Information
| Gene Symbol | CA14 |
| Gene ID | 23632 |
| Uniprot ID | CAH14_HUMAN |
| Accession Number | NP_036245 |
| Immunogen | Human |
| Immunogen Region | 16-290aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MGSADGGQHW TYEGPHGQDH WPASYPECGN NAQSPIDIQT DSVTFDPDLP ALQPHGYDQP GTEPLDLHNN GHTVQLSLPS TLYLGGLPRK YVAAQLHLHW GQKGSPGGSE HQINSEATFA ELHIVHYDSD SYDSLSEAAE RPQGLAVLGI LIEVGETKNI AYEHILSHLH EVRHKDQKTS VPPFNLRELL PKQLGQYFRY NGSLTTPP |
Additional Info
| Tissue Specificity | High expression in all parts of the central nervous system and lower expression in adult liver, heart, small intestine, colon, kidney, urinary bladder and skeletal muscle. |
| Function | Reversible hydration of carbon dioxide. |
| Protein Name | Carbonic Anhydrase 14Carbonate Dehydratase XivCarbonic Anhydrase XivCa-Xiv |
| Database Links | Reactome: R-HSA-1475029 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Protein Names | Carbonic Anhydrase 14 proteinCarbonate Dehydratase Xiv proteinCarbonic Anhydrase Xiv proteinCa-Xiv proteinCA14 proteinUNQ690 proteinPRO1335 protein |
Information sourced from Uniprot.org