Human CAPNS1 protein (Recombinant) (His-Tag) (STJP018777)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human CAPNS1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% Glycerol, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CAPNS1 |
| Gene ID | 826 |
| Uniprot ID | CPNS1_HUMAN |
| Accession Number | NP_001740 |
| Immunogen | Human |
| Immunogen Region | 84-268aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MGSRTHYSNI EANESEEVRQ FRRLFAQLAG DDMEVSATEL MNILNKVVTR HPDLKTDGFG IDTCRSMVAV MDSDTTGKLG FEEFKYLWNN IKRWQAIYKQ FDTDRSGTIC SSELPGAFEA AGFHLNEHLY NMIIRRYSDE SGNMDFDNFI SCLVRLDAMF RAFKSLDKDG TGQIQVNIQE WLQLTMYS |
Additional Info
| Function | Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Essential for embryonic development. |
| Protein Name | Calpain Small Subunit 1Css1Calcium-Activated Neutral Proteinase Small SubunitCanp Small SubunitCalcium-Dependent Protease Small SubunitCdpsCalcium-Dependent Protease Small Subunit 1Calpain Regulatory Subunit |
| Database Links | Reactome: R-HSA-1474228Reactome: R-HSA-6809371Reactome: R-HSA-8862803Reactome: R-HSA-9856530Reactome: R-HSA-9860927 |
| Cellular Localisation | CytoplasmCell MembraneTranslocates To The Plasma Membrane Upon Calcium Binding |
| Alternative Protein Names | Calpain Small Subunit 1 proteinCss1 proteinCalcium-Activated Neutral Proteinase Small Subunit proteinCanp Small Subunit proteinCalcium-Dependent Protease Small Subunit proteinCdps proteinCalcium-Dependent Protease Small Subunit 1 proteinCalpain Regulatory Subunit proteinCAPNS1 proteinCAPN4 proteinCAPNS protein |
Information sourced from Uniprot.org