Human CAPN6 protein (Recombinant) (N-His) (STJP006357)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CAPN6-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | CAPN6 |
| Gene ID | 827 |
| Uniprot ID | CAN6_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Leu26-Arg495 |
Additional Info
| Function | Microtubule-stabilizing protein that may be involved in the regulation of microtubule dynamics and cytoskeletal organization. May act as a regulator of RAC1 activity through interaction with ARHGEF2 to control lamellipodial formation and cell mobility. Does not seem to have protease activity as it has lost the active site residues. |
| Protein Name | Calpain-6Calpain-Like Protease X-LinkedCalpamodulinCalpm |
| Database Links | Reactome: R-HSA-1474228 |
| Cellular Localisation | CytoplasmPerinuclear RegionCytoskeletonSpindleDuring Mitose Associated With The Mitotic SpindleAt Telophase Colocalized To The Midbody Spindle |
| Alternative Protein Names | Calpain-6 proteinCalpain-Like Protease X-Linked proteinCalpamodulin proteinCalpm proteinCAPN6 proteinCALPM proteinCANPX protein |
Information sourced from Uniprot.org