Human CAPN2 (Calpain 2, Large Subunit) Sandwich ELISA Kit Ready-To-Use Kit (STJE0014048)
SPECIFICATIONS
General Information
| Short Description | This CAPN2 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.054ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 3 hrs |
Target Information
| Gene Symbol | CAPN2 |
| Gene ID | 824 |
| Uniprot ID | CAN2_HUMAN |
| Immunogen Region | Ready-To-Use |
| Sample Type | tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | Ubiquitous. |
| Post Translational Modifications | |
| Function | Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226'. Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs. |
| Protein Name | Calpain-2 Catalytic SubunitCalcium-Activated Neutral Proteinase 2Canp 2Calpain M-TypeCalpain Large Polypeptide L2Calpain-2 Large SubunitMillimolar-CalpainM-Calpain |
| Database Links | Reactome: R-HSA-1474228Reactome: R-HSA-8862803Reactome: R-HSA-9856530Reactome: R-HSA-9860927 |
| Cellular Localisation | CytoplasmCell MembraneTranslocates To The Plasma Membrane Upon Ca(2+) Binding |
| Alternative ELISA Names | Calpain-2 Catalytic Subunit ELISA kitCalcium-Activated Neutral Proteinase 2 ELISA kitCanp 2 ELISA kitCalpain M-Type ELISA kitCalpain Large Polypeptide L2 ELISA kitCalpain-2 Large Subunit ELISA kitMillimolar-Calpain ELISA kitM-Calpain ELISA kitCAPN2 ELISA kitCANPL2 ELISA kit |
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Information sourced from Uniprot.org