Human CAMLG protein (Recombinant) (His-Tag) (STJP018331)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human CAMLG-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CAMLG |
| Gene ID | 819 |
| Uniprot ID | CAMLG_HUMAN |
| Accession Number | NP_001736.1 |
| Immunogen | Human |
| Immunogen Region | 1-189aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Ubiquitous. Highest levels in brain, testis and ovary. |
| Function | Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET1/WRB, acts as a membrane receptor for soluble GET3/TRC40, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. Required for the stability of GET1. Stimulates calcium signaling in T cells through its involvement in elevation of intracellular calcium. Essential for the survival of peripheral follicular B cells. |
| Protein Name | Guided Entry Of Tail-Anchored Proteins Factor CamlgCalcium Signal-Modulating Cyclophilin Ligand |
| Database Links | Reactome: R-HSA-9609523 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Protein Names | Guided Entry Of Tail-Anchored Proteins Factor Camlg proteinCalcium Signal-Modulating Cyclophilin Ligand proteinCAMLG proteinCAML proteinGET2 protein |
Information sourced from Uniprot.org