Human Calneuron 1/CALN1 protein (Recombinant) (His-Tag) (STJP016912)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human Calneuron 1/CALN1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol, 2mM DTT, 50mM NaCl, 0.1mM PMSF |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CALN1 |
| Gene ID | 83698 |
| Uniprot ID | CABP8_HUMAN |
| Accession Number | NP_001017440 |
| Immunogen | Human |
| Immunogen Region | 1-192aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MPFHHVTAGL LYKGNYLNRS LSAGSDSEQL ANISVEELDE IREAFRVLDR DGNGFISKQE LGMAMRSLGY MPSEVELAII MQRLDMDGDG QVDFDEFMTI LGPKLVSSEG RDGFLGNTID SIFWQFDMQR ITLEELKHIL YHAFRDHLTM KDIENIIINE EESLNETSGN CQTEFEGVHS QKQNRQTCVR KS |
Additional Info
| Tissue Specificity | Brain specific. |
| Function | Negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. May play a role in the physiology of neurons and is potentially important in memory and learning. |
| Protein Name | Calcium-Binding Protein 8Cabp8Calneuron ICalneuron-1 |
| Database Links | |
| Cellular Localisation | Golgi ApparatusTrans-Golgi Network MembraneSingle-Pass Type Iv Membrane ProteinCytoplasmPerinuclear RegionCell Membrane |
| Alternative Protein Names | Calcium-Binding Protein 8 proteinCabp8 proteinCalneuron I proteinCalneuron-1 proteinCALN1 proteinCABP8 protein |
Information sourced from Uniprot.org