Human CALHM6 protein (Recombinant) (N-His) (STJP007653)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human CALHM6-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | CALHM6 |
| Gene ID | 441168 |
| Uniprot ID | CAHM6_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Arg197-Ile309 |
Additional Info
| Post Translational Modifications | N-glycosylated. |
| Function | Pore-forming subunit of an ATP-permeable channel. In response to pathogen-derived and proinflammatory stimuli, relocates from intracellular compartments to NK-dendritic cell and NK-macrophage immune synapses where it mediates ATP efflux and NK cell activation involved in antimicrobial and antitumor responses. May assemble to form gap junction channel-like structures with gating and ion conductance likely regulated by membrane lipids and voltage rather than by extracellular calcium levels. |
| Protein Name | Calcium Homeostasis Modulator Protein 6Protein Fam26f |
| Database Links | |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinRecruited At Immune Synapses In Response To Pathogen-Derived And Proinflammatory Stimuli |
| Alternative Protein Names | Calcium Homeostasis Modulator Protein 6 proteinProtein Fam26f proteinCALHM6 proteinC6orf187 proteinFAM26F protein |
Information sourced from Uniprot.org