Human Calcium Activated Nucleotidase 1/CANT1 protein (Recombinant) (His-Tag) (STJP017461)

SPECIFICATIONS
HostE.coli
ImmunogenHuman
STJP017461
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General Information

Short DescriptionRecombinant-Human Calcium Activated Nucleotidase 1/CANT1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration1 mg/mL
FormulationLiquid in 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% Glycerol, 50mM NaCl
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolCANT1
Gene ID124583
Uniprot IDCANT1_HUMAN
Accession NumberNP_620148
ImmunogenHuman
Immunogen Region63-401aa
Immunogen SequenceMGSSHHHHHH SSGLVPRGSH MGSHMRPAPG RPPTHNAHNW RLGQAPANWY NDTYPLSPPQ RTPAGIRYRI AVIADLDTES RAQEENTWFS YLKKGYLTLS DSGDKVAVEW DKDHGVLESH LAEKGRGMEL SDLIVFNGKL YSVDDRTGVV YQIEGSKAVP WVILSDGDGT VEKGFKAEWL AVKDERLYVG GLGKEWTTTT GDVVNENPEW VKVVGYKGSV DHENWVSN

Additional Info

Tissue Specificity Widely expressed.
Post Translational Modifications N-glycosylated.
Function Calcium-dependent nucleotidase with a preference for UDP. The order of activity with different substrates is UDP > GDP > UTP > GTP. Has very low activity towards ADP and even lower activity towards ATP. Does not hydrolyze AMP and GMP. Involved in proteoglycan synthesis.
Protein Name Soluble Calcium-Activated Nucleotidase 1
Scan-1
Apyrase Homolog
Putative Mapk-Activating Protein Pm09
Putative Nf-Kappa-B-Activating Protein 107
Database Links Reactome: R-HSA-6798695
Cellular Localisation Endoplasmic Reticulum Membrane
Single-Pass Type Ii Membrane Protein
Golgi Apparatus
Golgi Stack Membrane
Cell Membrane
Processed Form: Secreted
Alternative Protein Names Soluble Calcium-Activated Nucleotidase 1 protein
Scan-1 protein
Apyrase Homolog protein
Putative Mapk-Activating Protein Pm09 protein
Putative Nf-Kappa-B-Activating Protein 107 protein
CANT1 protein
SHAPY protein

Information sourced from Uniprot.org

Citations

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