Human Calcipressin-1/DSCR1 protein (Recombinant) (No-Tag) (STJP019614)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human Calcipressin-1/DSCR1-No-Tag protein was developed from e.coli and has a target region of No-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 7.5) containing 0.1M NaCl, 1mM DTT, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | RCAN1 |
| Gene ID | 1827 |
| Uniprot ID | RCAN1_HUMAN |
| Accession Number | NP_981962.1 |
| Immunogen | Human |
| Immunogen Region | 1-117aa |
| Immunogen Sequence | MKLYFAQTLH IGSSHLAPPN PDKQFLISPP ASPPVGWKQV EDATPVINYD LLYAISKLGP GEKYELHAAT DTTPSVVVHV CESDQEKEEE EEMERMRRPK PKIIQTRRPE YTPIHLS |
Additional Info
| Tissue Specificity | Highly expressed heart, brain and skeletal muscle. Also expressed in all other tissues. |
| Post Translational Modifications | Phosphorylation increases its ability to inhibit calcineurin and decreases protein half-life. |
| Function | Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development. |
| Protein Name | Calcipressin-1Adapt78Down Syndrome Critical Region Protein 1Myocyte-Enriched Calcineurin-Interacting Protein 1Mcip1Regulator Of Calcineurin 1 |
| Database Links | |
| Cellular Localisation | |
| Alternative Protein Names | Calcipressin-1 proteinAdapt78 proteinDown Syndrome Critical Region Protein 1 proteinMyocyte-Enriched Calcineurin-Interacting Protein 1 proteinMcip1 proteinRegulator Of Calcineurin 1 proteinRCAN1 proteinADAPT78 proteinCSP1 proteinDSC1 proteinDSCR1 protein |
Information sourced from Uniprot.org