Human CACYBP protein (Recombinant) (His-Tag) (STJP016706)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human CACYBP-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol, 1mM DTT, 0.1M NaCl. |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CACYBP |
| Gene ID | 27101 |
| Uniprot ID | CYBP_HUMAN |
| Accession Number | NP_001007215 |
| Immunogen | Human |
| Immunogen Region | 1-185aa |
| Immunogen Sequence |
Additional Info
| Post Translational Modifications | Phosphorylated on serine residues. Phosphorylated upon induction by RA or at high calcium concentrations. |
| Function | May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1). |
| Protein Name | Calcyclin-Binding ProteinCacybpHcacybpS100a6-Binding ProteinSiah-Interacting Protein |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmCytoplasmic At Low Calcium ConcentrationsIn Neuroblastoma CellsAfter A Retinoic Acid (Ra) Induction And Calcium IncreaseIt Localizes In Both The Nucleus And CytoplasmThe Nuclear Fraction May Be Phosphorylated |
| Alternative Protein Names | Calcyclin-Binding Protein proteinCacybp proteinHcacybp proteinS100a6-Binding Protein proteinSiah-Interacting Protein proteinCACYBP proteinS100A6BP proteinSIP proteinPNAS-107 protein |
Information sourced from Uniprot.org