Human C1QTNF12 protein (Recombinant) (N-His) (STJP006677)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human C1QTNF12-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | C1QTNF12 |
| Gene ID | 388581 |
| Uniprot ID | ADIPL_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Gly92-Gln241 |
Additional Info
| Post Translational Modifications | Processed into Adipolin fC1QTNF12 and Adipolin gC1QTNF12 by FURIN. Insulin enhances endogenous C1QTNF12 cleavage. |
| Function | Insulin-sensitizing adipocyte-secreted protein (adipokine) that regulates glucose metabolism in liver and adipose tissue. Promotes glucose uptake in adipocytes and suppresses de novo glucose production in hepatocytes via the PI3K-Akt signaling pathway. Administration lead to reduction of blood glucose. Able to attenuate inflammation in fat tissue. |
| Protein Name | AdipolinAdipose-Derived Insulin-Sensitizing FactorC1q And Tnf Related Protein 12Complement C1q Tumor Necrosis Factor-Related Protein 12 Cleaved Into - Adipolin Fc1qtnf12Adipolin Fctrp12Adipolin Full-Length Form - Adipolin Gc1qtnf12Adipolin Cleaved FormAdipolin Gctrp12 |
| Database Links | |
| Cellular Localisation | Adipolin Fc1qtnf12: SecretedAdipolin Gc1qtnf12: SecretedIn Sera Is The Predominant Form |
| Alternative Protein Names | Adipolin proteinAdipose-Derived Insulin-Sensitizing Factor proteinC1q And Tnf Related Protein 12 proteinComplement C1q Tumor Necrosis Factor-Related Protein 12 Cleaved Into - Adipolin Fc1qtnf12 proteinAdipolin Fctrp12 proteinAdipolin Full-Length Form - Adipolin Gc1qtnf12 proteinAdipolin Cleaved Form proteinAdipolin Gctrp12 proteinC1QTNF12 proteinC1QDC2 proteinCTRP12 proteinFAM132A protein |
Information sourced from Uniprot.org